Discovery of a structural class of antibiotics with explainable deep learning.
One of the challenges with deep learning (neural networks) is that although they find patterns the reasoning disappears into an endless detail of numbers. In this paper the researchers built an 'explainable' AI to discover antibiotics instead of such a 'black box'. "The discovery of novel structural...
Source: nature.com
High Pay Centre analysis of FTSE 350 pay ratios • High Pay Centre
Pay inequalities at UK's largest companies remain constant, despite ‘cost of living’ crisis. "The companies with lowest-paid UK employees (based on pay at the 25th percentile) were retailer JD Sports, where the lower quartile threshold was £11,240, pub chain Mitchells & Butlers (£15,161) and...
Source: highpaycentre.org
Search algorithm reveals nearly 200 new kinds of CRISPR systems Allessandra DiCorato | Broad Institute.
A new search algorithm has identified 188 kinds of new CRISPR systems in bacterial genomes. The systems have a range of functions and could enable gene editing, diagnostics, and more.
Source: mit.edu
A guide to 9 global buzzwords for 2023, from 'polycrisis' to 'zero-dose children'
Are you having a polycrisis? Can the world reduce the number of zero-dose children? Experts shared their views about global buzzwords that will be big this year. Here's the list and the definitions.
Source: npr.org
Video: Bison roam England again for the first time in thousands of years
European bison were released in Kent this morning to boost biodiversity and tackle the climate crisis. The timing is pertinent
Source: positive.news
Senior health professionals call for urgent climate briefing of all MPs by the chief scientific adviser: open letter to
Dear prime minister,
We wish to make you aware of our concern for the health of Angus Rose, a 52 year old man, who at the time of writing is on day 34 of a hunger strike outside Parliament, consuming only fluids, vitamins, and minerals.
His not unreasonable demand is that all members of parliament...
Source: bmj.com
Biopharma futures
I've been looking at a few industry reports on the future of biopharma as part of a course I'm on with INSEAD Business School on Business Strategy and Financial Performance. I thought I'd share some of my ramblings on Biopharma Futures. Expectations are high Pharmaceutical
companies are operating...
Source: agnate.co.uk
6 expert essays on the future of biotech
How will biotechnology transform our approach to human health? Scientists from the World Economic Forum's Global Future Council share key insights. World Economic Forum future of biotech DNA technology - genetic screening for disease, recombinant protein production, CAR T cells, gene therapy, organoid...
Source: weforum.org
Biopharma 2020: A landmark year and a reset for the future
Biopharma in 2020 has shown what it can achieve when it works at its best. How can the industry build on this renewed sense of purpose in the years ahead? McKinsey biopharma 2020 3 Overarching trends Operating under a spotlight - expectation of innovationNavigating protracted economic uncertainty -...
Source: mckinsey.com
Psychology of panic buying
I've been fascinated by the psychology of panic buying and it is clearly an area for future research. It has an enormous impact on delivery infrastructure and I wonder if anyone has been tracking the data of the causes and the impact in the current fuel 'crisis'. A systematic review from last year identified...
Source: nih.gov
Effectiveness of a serious game addressing guideline adherence: cohort study with 1.5-year follow-up Tobias Raupach. Insa
Background Patients presenting with acute shortness of breath and chest pain should be managed according to guideline recommendations. Serious games can be used to train clinical reasoning. However, only few studies have used outcomes beyond student satisfaction, and most of the published evidence is...
Source: biomedcentral.com
5 failures of political leaders during a public health crisis
“There are five traps political leaders can fall into when it comes to a public health emergency: 1. delay and downplay; 2. fudge the science; 3. isolation from the international community; 4. absence; and 5. double standards.” Sophie Harman Professor of International Politics at Queen Mary University...
Source: qmul.ac.uk
Build for a crisis: Ideas for the future of local news
Enjoyed this story of the ingenuity of local newspapers when struck with the crisis of extreme weather. What does it say for our other complex technology and business layers? When crisis strikes perhaps that's when you find the lowest common tech that works and exactly what purpose you are using it for....
Source: niemanlab.org
Raise benefits to curb UK crisis in mental health, expert urges
Sir Michael Marmot says ‘uncaring’ system must be made more generous to bridge growing gap in health inequality
Source: theguardian.com
Opinion: The UK has a huge rubbish problem – but building new waste incinerators isn’t the answer
Some take waste directly from businesses, but the vast majority burn the contents of our wheelie bins – and around 12 per cent of that is plastic
Source: independent.co.uk
Declining Life Expectancy in the United States
This Viewpoint reviews the social and economic drivers of declines in longevity in the US, especially among lower socioeconomic status groups, and proposes policy options for the Biden-Harris administration to mitigate the trend, including an increase in the federally mandated minimum wage. Atheendar...
Source: jamanetwork.com
Covid-19: The global crisis — in data: Charts and maps show paradoxes of a pandemic that has claimed a million lives
Covid-19: The global crisis — in data: Charts and maps show paradoxes of a pandemic that has claimed a million lives
Source: ig.ft.com
Dying in a Leadership Vacuum Why has the United States handled this pandemic so badly?
Dying in a Leadership Vacuum Why has the United States handled this pandemic so badly? The NEJM Editors asks what has gone so wrong in the US and lays the blame with the political leadership. "This crisis has produced a test of leadership. With no good options to combat a novel pathogen, countries were...
Source: nejm.org
7 Predictions for a Post-Coronavirus World
1. Companies that traffic in digital services and e-commerce will make immediate and lasting gains 2. Remote work will become the default 3. Many jobs will be automated, and the rest will be made remote-capable 4. Telemedicine will become the new normal, signaling an explosion in med-tech innovation...
Source: medium.com
Media predictions for 2020 from BBC's Amol Rajan
Amol Rajan's 9 media predictions for 2020: Could we see streamageddon, eco-browsing, the break-up of Amazon and a new owner for ITV? "The data shows we really are living through the most extraordinarily peaceful, prosperous, wealthy, healthy, safe period in human history. There is strong evidence to...
Source: bbc.com
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