Imperial College's COVID-19 modelling
Report 9: Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand. "We show that in the UK and US context, suppression will minimally require a combination of social distancing of the entire population, home isolation of cases and household quarantine of their...
Source: imperial.ac.uk
Coronavirus COVID-19 SARS-CoV-2 information
A collection of information sources for COVID-19. The NHS 111 online COVID-19 service. The first point of call for someone in the UK who thinks they have symptoms or have been exposed whilst travelling. The NHS Coronavirus COVID-19 information webpage. UK Government's Coronavirus action plan. Public...
Apple Abandoned Encrypted iCloud Backups After FBI Intervened
"Apple Abandoned Encrypted iCloud Backups After FBI Intervened - ExtremeTech: According to a new report, Apple dropped plans that would have made user data even more secure by encrypting backups. It made this course change after the FBI quietly expressed concern that it could harm investigations." Companies...
Source: extremetech.com
UCL cancer policy update
“Because of the complexity of delivering better cancer care and the dynamics of NHS funding and introducing better practices in the health service there is a strong case for developing new cancer strategies for all the UK nations for the 2020s. Britain could also benefit from leading an independent...
Source: ucl.ac.uk
Early warning signals for critical transitions in a thermoacoustic system:
Early warning signals for critical transitions in a thermoacoustic system: Dynamical systems can undergo critical transitions where the system suddenly shifts from one stable state to another at a critical threshold called the tipping point. The decrease in recovery rate to equilibrium (critical slowing...
Source: nature.com
Eisai launches a digital health solution on Amazon Alexa for children with a rare form of epilepsy - Lennox-Gastaut Syndrome.
It marks the first time Pharmaceutical company Eisai has moved beyond medications and into digital health. The company’s Amazon Alexa skill – Ella the Jellyfish – has been developed for children with Lennox-Gastaut Syndrome (LGS) and was created with input from patients, their families and caregivers.
Source: epmmagazine.com
Publication bias is a challenge in science and a criticism of the influence of industry.
Publication bias is a challenge in science and a criticism of the influence of industry. In the domain of biosciences and drug development more accountability (e.g. the FDAAA 2007), editorial and peer-review training (as suggested by the Cochrane Collaboration), and statistical techniques (as championed...
A critical makeover for pharmaceutical companies: Overcoming industry obstacles with a cross-functional strategy. PwC
A critical makeover for pharmaceutical companies: Overcoming industry obstacles with a cross-functional strategy. PwC report. Going all "cross-functional" or "breaking down silos"?
"Compounding the external obstacles, however, is the internal culture of most pharma companies. This is an industry...
Source: pwc.com
Benefits and harms of exercise programmes for people with ankylosing spondylitis. Cochrane review. "We found moderate- to
Benefits and harms of exercise programmes for people with ankylosing spondylitis. Cochrane review. "We found moderate- to low-quality evidence that exercise programmes probably slightly improve function, may reduce pain, and probably slightly reduce global patient assessment of disease activity, when...
Source: cochrane.org
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’
Development of new antibiotics encouraged with new pharmaceutical payment system: The NHS will test the world's first ‘subscription’ style payment model to incentivise pharmaceutical companies to develop new drugs for resistant infections.
"The new trial will be led by the National Institute for...
Source: www.gov.uk
Utility of social media and crowd-intelligence data for pharmacovigilance: a scoping review. - PubMed - NCBI "Although
Utility of social media and crowd-intelligence data for pharmacovigilance: a scoping review. - PubMed - NCBI "Although social media data has the potential to supplement data from
regulatory agency databases; is able to capture less frequently reported
AEs; and can identify AEs earlier than official...
Source: nih.gov
EU Trials Tracker — Who's not sharing clinical trial results? : By law, all clinical trials on the European Union
EU Trials Tracker — Who's not sharing clinical trial results?
:
By law, all clinical trials on the European Union Clinical Trials Register
(EUCTR) must report their results in the registry within a year of completion.
This site tracks which universities and pharmaceutical companies are...
Source: trialstracker.net
Is pharma rolling in cash or on the brink of a long-term decline? - Healthcare Economist "Although successful drugs often
Is pharma rolling in cash or on the brink of a long-term decline? - Healthcare Economist "Although successful drugs often are expensive, most drugs fail. Thus, while the returns from a blockbuster drug are large, returns from a companies’ entire portfolio may be very modest. Additionally, finding...
Source: healthcare-economist.com
Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound,
Early phase drug trial claims a breakthrough in Huntington disease. IONIS-HTT is an antisense "gene-silencing" compound, injected in to CSF and designed to reduce the production of all forms of the huntingtin (HTT) protein, which in its mutated variant (mHTT) is responsible for Huntington's Disease....
Source: reuters.com
Three-Quarters of All Honey On Earth Has Pesticides In It - Slashdot: An anonymous reader quotes a report from The Verge:
Three-Quarters of All Honey On Earth Has Pesticides In It - Slashdot: An anonymous reader quotes a report from The Verge: About three quarters of all honey worldwide is contaminated with pesticides known to harm bees, according to a new study. Though the pesticide levels were below the limit deemed safe...
Source: slashdot.org
Police raid Merck pharmaceutical plant amid mysterious drug crisis: Is something wrong with hormone therapy or are patients
Police raid Merck pharmaceutical plant amid mysterious drug crisis: Is something wrong with hormone therapy or are patients over-reacting?
Source: arstechnica.com
The Movie “Cholesterol: The Great Bluff” Is an Exercise in Denialism: The movie “Cholesterol: The Great Bluff” claims
The Movie “Cholesterol: The Great Bluff” Is an Exercise in Denialism: The movie “Cholesterol: The Great Bluff” claims that we have been lied to: cholesterol doesn’t cause heart disease and statins are harmful. It is biased and misleading. The peopl…
Source: sciencebasedmedicine.org
Abstinence-Only-Until-Marriage Programs and Policies are a Failure | Columbia University Mailman School of Public Health
Abstinence-Only-Until-Marriage Programs and Policies are a Failure | Columbia University Mailman School of Public Health "Two scientific review papers released today show that abstinence-only-until-marriage programs and policies in the United States are ineffective as they do not delay sexual initiation...
Source: columbia.edu
Cost Effectiveness of Support for People Starting a New Medication for a Long-Term Condition Through Community Pharmacies:
Cost Effectiveness of Support for People Starting a New Medication for a Long-Term Condition Through Community Pharmacies: An Economic Evaluation of the New Medicine Service (NMS) Compared with Normal Practice Rachel A. Elliott. Lukasz Tanajewski. Georgios Gkountouras. Anthony J. Avery. Nick Barber....
Source: springer.com
1 in 12 doctors accepts payment from pharmaceutical companies related to opioids: One in twelve physicians -- and nearly
1 in 12 doctors accepts payment from pharmaceutical companies related to opioids: One in twelve physicians -- and nearly one in five family medicine physicians -- accepted payments from pharmaceutical companies related to opioids, according to a new study out of Boston Medical Center's Grayken Center...
Source: eurekalert.org
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