65 Reasons To Celebrate The 6502
"The legendary chip from 1975 that helped start the home computer revolution." I can remember sharing the manual for the 6502 with my school friend, Chris. He had a BBC micro computer and I had a Commodore Vic 20. To do the machine code I remember you had to: compile into 6502 instructions what you...
Source: substack.com
Integrating basic sciences into clerkship rotation utilizing Kern’s six-step model of instructional design: lessons learned
Worked example of curriculum design using Kern's six-step approach. "Background It is generally agreed that basic and clinical sciences should be integrated throughout the undergraduate medical education, however, there is still need for continued formal integration of basic sciences into clinical...
Source: biomedcentral.com
Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations
"The last 10,000 years have seen some of the most extreme global changes in lifestyle, with the emergence of farming in some regions and pastoralism in others. While 5,000 years ago farmer ancestry predominated across Europe, a relatively diverged genetic ancestry arrived with the steppe migrations around...
Source: nature.com
Isomorphic Labs kicks off 2024 with two pharmaceutical collaborations - Isomorphic Labs
Isomorphic Labs kicks off 2024 with two pharmaceutical collaborations
Source: isomorphiclabs.com
Discovery of a structural class of antibiotics with explainable deep learning.
One of the challenges with deep learning (neural networks) is that although they find patterns the reasoning disappears into an endless detail of numbers. In this paper the researchers built an 'explainable' AI to discover antibiotics instead of such a 'black box'. "The discovery of novel structural...
Source: nature.com
These six questions will dictate the future of generative AI
Generative AI took the world by storm in 2023. Its future—and ours—will be shaped by what we do next. TL;DR 1. Will we ever mitigate the bias problem? (Probably) 2. How will AI change the way we apply copyright? (A lot) 3. How will it change our jobs? (Maybe not as much as feared but things will...
Source: technologyreview.com
The rise of the AI class
"In an industry shedding publishers and jobs and routinely challenged to do more with less, we’re foolish not to at least try on the generative AI suit."
Source: niemanlab.org
“Meet the patient” session: a strategy to teach medical students about autonomic dysfunction after spinal cord injury
Dysregulation of the autonomic nervous system is an important long-term consequence of spinal cord injury (SCI). Yet, there is a scarcity of teaching resources about this topic for preclinical medical students. Given the association of SCI sequelae with emergency complications and mortality, it is imperative...
Source: biomedcentral.com
QR codes to become less convenient?
A sticker with a fraudulent QR code pasted over a legitimate one can lead the unwary to websites that can capture your personal data. Thornaby: Woman targeted in £13k train station QR code scam. Rail firm TransPennine Express has since removed QR codes from all of its station car parks. Is the root...
Source: bbc.com
Recent waning snowpack in the Alps is unprecedented in the last six centuries - Nature Climate Change Carrer, Marco. Dibona,
Snow cover in high-latitude and high-altitude regions has strong effects on the Earth’s climate, environmental processes and socio-economic activities. Over the last 50 years, the Alps experienced a 5.6% reduction per decade in snow cover duration, which already affects a region where economy and...
Source: nature.com
Tax Filing Websites Caught Sending Users' Financial Data to Facebook - ExtremeTech
Filing status, dependent names, adjusted gross income...once it's on any of these three websites, it's likely in Facebook's hands. ”H&R Block, one of the country’s most recognizable tax filing firms, was found using Meta Pixel to obtain users’ health savings account usage data as well as dependents’...
Source: extremetech.com
FDA approves most expensive drug ever, a $3.5 million-per-dose gene therapy for hemophilia B
The single-dose medicine "represents important progress" as the first-ever gene therapy for the rare disorder, the FDA said. ”The Food and Drug Administration cleared Hemgenix, an IV treatment for adults with hemophilia B, the less common form of the genetic disorder which primarily affects men.”
Source: cbsnews.com
Aymptomatic testing for COVID could reduce hospital admissions
"The city-wide pilot of community based asymptomatic testing for SARS-CoV-2 was associated with substantially reduced covid-19 related hospital admissions. Large scale asymptomatic rapid testing for SARS-CoV-2 could help reduce transmission and prevent hospital admissions."
Source: bmj.com
The International Code of Medical Ethics of the World Medical Association Ramin Walter Parsa-Parsi. JAMA.
"One of the central missions of the World Medical Association (WMA) in its role as the global organization of physicians is to ensure the highest possible standard of ethical practice of the medical profession. Since its establishment in 1947 in the aftermath of one of the most egregious breaches of...
Source: jamanetwork.com
Mind-controlled wheelchairs let people dodge obstacles with ease Nature 2022.
A brain—machine interface allows people with paralysis in all four limbs to navigate a real-world environment. A brain—machine interface allows people with paralysis in all four limbs to navigate a real-world environment.
Source: nature.com
Therese Coffey tells health workers about her 'working preferences'
New Health Secretary issues guidance telling staff of her 'working preferences' ... this includes: - stop using the Oxford comma - avoid double negatives - be 'positive' - to steer clear of 'jargon' After the incredible work that the NHS did in response to the pandemic and the sacrifices many staff...
Source: telegraph.co.uk
The UK’s (new) Bill of Rights
An authoritarian resistance to scrutiny. Very un-British.
“it is becoming abundantly clear that the true objective underpinning this Bill (and the Government’s wider project) concerns not the so-called restoration of parliamentary sovereignty or the strengthening of democracy, but the entrenchment...
Source: publiclawforeveryone.com
Fleeing Russian bombs while battling Facebook. A Meta problem Ukrainian journalists did not need. - Coda Story
The challenge of local journalism and of censoring during war. "Facebook says it’s fighting disinformation and blocking Russian propaganda. But independent newsrooms in eastern Ukraine say they’re being restricted under the same rules."
Source: codastory.com
House passes $35-a-month insulin cap as Dems seek wider bill
WASHINGTON (AP) — The House on Thursday passed a bill capping the monthly cost of insulin at $35 for insured patients, part of an election-year push by Democrats for price curbs on prescription drugs at a time of rising inflation.
Source: apnews.com
The Bluestocking: The Ant Mill
The Ant Mill theory of Discourse. "An orphan take is an opinion expressed in backlash to a marginal, nebulous or anticipated opposing view. If you see angry tweets or opeds about the horror of a viewpoint you’ve never seen expressed in the wild, that’s an orphan take."
Source: substack.com
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