Discovery of a structural class of antibiotics with explainable deep learning.
One of the challenges with deep learning (neural networks) is that although they find patterns the reasoning disappears into an endless detail of numbers. In this paper the researchers built an 'explainable' AI to discover antibiotics instead of such a 'black box'. "The discovery of novel structural...
Source: nature.com
Association of the “Weekend Warrior” and Other Leisure-time Physical Activity Patterns With All-Cause and Cause-Specific
This large prospective cohort study of US adults examines whether performing the recommended level of physical activity throughout the week or in fewer days, such as the weekend, influences all-cause, cardiovascular disease, or cancer mortality.
Source: jamanetwork.com
Effectiveness of a serious game addressing guideline adherence: cohort study with 1.5-year follow-up Tobias Raupach. Insa
Background Patients presenting with acute shortness of breath and chest pain should be managed according to guideline recommendations. Serious games can be used to train clinical reasoning. However, only few studies have used outcomes beyond student satisfaction, and most of the published evidence is...
Source: biomedcentral.com
Using GPT-2 to generate Tweets
Last summer I blogged about using a Deep Neural Network to generate tweets but only used 3200 of my tweets. Since then I've used Twitter's archive mechanism to retrieve ALL my tweets (just over 30,000) to train a network. Not any old network - the GPT-2 model from OpenAI. This 'finetuning' of an existing...
IEA says global CO2 emissions rising again after nearly 6% fall last year
"Global carbon dioxide emissions dropped by 5.8% in 2020 as the COVID-19 pandemic slowed economic activity, but they rebounded at the end of the year and are on course to rise further, the International Energy Agency said on Tuesday." Whilst economic growth is sought to reduce national deficits following...
Source: reuters.com
Is the UK destined to be the next life science hub?
Jason Shafrin explores the question in The Economist about the role of British science in the pandemic and the future of the UK life sciences activity.
"With good data, efficient regulation, an international collection of talent, R&D funds focused on the health care, the UK could see big gains...
Source: healthcare-economist.com
Most brain activity is "background noise"
"Most brain activity is "background noise" and that's upending our understanding of consciousness." This complexity view of the mind is not new but this article explains it quite clearly.
Source: salon.com
Preventing critical failure
Can routinely collected data be repurposed to predict avoidable patient harm? A quantitative descriptive study Objectives To determine whether sharing of routinely collected health service performance data could have predicted a critical safety failure at an Australian maternity service. Design Observational...
Source: bmj.com
Proposal for a New Tool to Evaluate a Serious Game
Proposal for a New Tool to Evaluate a Serious Game: The current enthusiasm of generations of students for video games and the marked interest of training institutions for the use of playful strategies, which facilitate learning, has encouraged the development and use of formative games called Serious...
Source: online-journals.org
SARS-CoV-2-specific T cell immunity is seen in cases of COVID-19
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls: Memory T cells induced by previous pathogens can shape the susceptibility to, and clinical severity of, subsequent infections1. Little is known about the presence of pre-existing memory T cells in humans with...
Source: nature.com
Evaluation of Mobile Apps Targeted at Patients With Spondyloarthritis for Disease Monitoring: Systematic App Search.
Evaluation of Mobile Apps Targeted at Patients With Spondyloarthritis for Disease Monitoring. "A total of 1253 apps were identified in the app stores, and 5 apps met the criteria and were further analyzed. Moreover, 2 apps (MySpA and Group for Research and Assessment of Psoriasis and Psoriatic Arthritis...
Source: nih.gov
Benefits and harms of exercise programmes for people with ankylosing spondylitis. Cochrane review. "We found moderate- to
Benefits and harms of exercise programmes for people with ankylosing spondylitis. Cochrane review. "We found moderate- to low-quality evidence that exercise programmes probably slightly improve function, may reduce pain, and probably slightly reduce global patient assessment of disease activity, when...
Source: cochrane.org
Unnecessarily difficult: Physical activity resources for adults are loaded with jargon: Web page articles and other written
Unnecessarily difficult: Physical activity resources for adults are loaded with jargon: Web page articles and other written materials designed to encourage physical activity are often too difficult to be easily read and understood by most US adults, limiting their effectiveness.
Source: eurekalert.org
Simulation based education and expansive learning in health professional education: A discussion: The aim of this paper
Simulation based education and expansive learning in health professional education: A discussion: The aim of this paper is to discuss the application of Simulation Based Education (SBE) in nursing and wider health professional education. Simulated Learning (SL) is discussed in relation to its history,...
Source: journals.sfu.ca
Reflection revisited: how physicians conceptualize and experience reflection in professional practice - a qualitative study:
Reflection revisited: how physicians conceptualize and experience reflection in professional practice - a qualitative study: For the purpose of continuous performance improvement, physicians are expected to reflect on their practice. While many reflection studies are theoretically oriented and often...
Source: biomedcentral.com
Content validation of an interprofessional learning video peer assessment tool: Large scale models of interprofessional
Content validation of an interprofessional learning video peer assessment tool: Large scale models of interprofessional learning (IPL) where outcomes are assessed are rare within health professional curricula. To date, there is sparse research describing robust assessment strategies to support such activities....
Source: biomedcentral.com
Small increases in physical activity reduce immobility, disability risks in older adults: Adding 48 minutes of exercise
Small increases in physical activity reduce immobility, disability risks in older adults: Adding 48 minutes of exercise per week is associated with improvements in overall mobility and decreases in risks of disability in older adults who are sedentary, finds a new study led by researchers at the Jean...
Source: eurekalert.org
The burden of triumph: meeting health and social care needs. Andrew Dilnot, Lancet 15 August 2017. "Life is getting longer.
The burden of triumph: meeting health and social care needs. Andrew Dilnot, Lancet 15 August 2017. "Life is getting longer. Death is not defeated, but it takes longer to win than it used to. The increases seen for most people in life expectancy are surely a matter for great rejoicing. References to...
Source: thelancet.com
GPs in England 'unconfident' discussing physical activity with patients – report: Less than two-thirds of doctors feel
GPs in England 'unconfident' discussing physical activity with patients – report: Less than two-thirds of doctors feel confident discussing activity levels and almost a third have never heard of national guidelines. "The majority of doctors in England are unfamiliar with recommended
levels of physical...
Source: theguardian.com
Important for GPs to be aware of up to date clinical guidelines around physical activity, says RCGP
Important for GPs to be aware of up to date clinical guidelines around physical activity, says RCGP
Source: rcgp.org.uk
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