Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16%...
Source: nature.com
Biopharma futures
I've been looking at a few industry reports on the future of biopharma as part of a course I'm on with INSEAD Business School on Business Strategy and Financial Performance. I thought I'd share some of my ramblings on Biopharma Futures. Expectations are high Pharmaceutical
companies are operating...
Source: agnate.co.uk
Biopharma 2020: A landmark year and a reset for the future
Biopharma in 2020 has shown what it can achieve when it works at its best. How can the industry build on this renewed sense of purpose in the years ahead? McKinsey biopharma 2020 3 Overarching trends Operating under a spotlight - expectation of innovationNavigating protracted economic uncertainty -...
Source: mckinsey.com
The future of biopharma
Shifts in how diseases are diagnosed and prevented, custom treatments, curative therapies, digital therapeutics, and precision intervention could upend current business models in biopharma. Deloitte's Five forces to 2040 Prevention and early detection Customized treatments - interventions for very...
Source: deloitte.com
Psychology of panic buying
I've been fascinated by the psychology of panic buying and it is clearly an area for future research. It has an enormous impact on delivery infrastructure and I wonder if anyone has been tracking the data of the causes and the impact in the current fuel 'crisis'. A systematic review from last year identified...
Source: nih.gov
The Impact of Mask Distribution and Promotion on Mask Uptake and COVID-19 in Bangladesh
A growing body of scientific evidence suggests that face masks can protect against COVID-19. There is, however, limited rigorous evidence on the extent to which mask-wearing is effective in reducing COVID-19 in a real-life situation with imperfect and inconsistent mask use. In Bangladesh, researchers...
Source: poverty-action.org
Development and validation of teacher and student questionnaires measuring inhibitors of curriculum viability - BMC Medical
Background Curriculum viability is determined by the degree to which quality standards have or have not been met, and by the inhibitors that affect attainment of those standards. The literature reports many ways to evaluate whether a curriculum reaches its quality standards, but less attention is paid...
Source: biomedcentral.com
China’s GPT-3? BAAI Introduces Superscale Intelligence Model ‘Wu Dao 1.0’ | Synced
The Beijing Academy of Artificial Intelligence (BAAI) releases Wu Dao 1.0, China’s first large-scale pretraining model.
Source: syncedreview.com
No Evidence That Associations Between Adolescents' Digital Technology Engagement and Mental Health Problems Have Increased
Digital technology is ubiquitous in modern adolescence, and researchers are concerned that it has negative impacts on mental health that, furthermore, increase over time. To investigate whether technology is becoming more harmful, we examined changes in associations between technology engagement and...
Source: sagepub.com
AI unlocks ancient Dead Sea Scrolls mystery
"Cutting edge technology" reveals how scribes foiled modern scholars with one of the Biblical texts.
Source: bbc.com
It just got a little easier to move your Facebook posts to some other platform
Social networks have typically followed the roach motel model of customer data: Make it easy to push data in, but hard/impossible to pull it back out. Platforms like Facebook, LinkedIn, Instagram, and Twitter all make money by knowing what information you've (wittingly or unwittingly) handed over ââ¦
Source: niemanlab.org
Constructing Transformers For Longer Sequences with Sparse Attention Methods
"We show that carefully designed sparse attention can be as expressive and flexible as the original full attention model. Along with theoretical guarantees, we provide a very efficient implementation which allows us to scale to much longer inputs. As a consequence, we achieve state-of-the-art results...
Source: googleblog.com
Using Markov chain model to evaluate medical students’ trajectory on progress tests and predict USMLE step 1 scores---a
Background Medical students must meet curricular expectations and pass national licensing examinations to become physicians. However, no previous studies explicitly modeled stages of medical students acquiring basic science knowledge. In this study, we employed an innovative statistical model to characterize...
Source: biomedcentral.com
Guest Post - A Model for Peer-to-Peer Workplace Learning - The Scholarly Kitchen
Gabe Harp discusses MIT Press' 'Skill Exchange', a peer to peer program to foster learning and professional development.
Source: sspnet.org
Detection of a particle shower at the Glashow resonance with IceCube Nature.
The Glashow resonance describes the resonant formation of a W− boson during the interaction of a high-energy electron antineutrino with an electron1, peaking at an antineutrino energy of 6.3 petaelectronvolts (PeV) in the rest frame of the electron. Whereas this energy scale is out of reach for currently...
Source: nature.com
The role of motivational profiles in learning problem-solving and self-assessment skills with video modeling examples Lisette
In the current study, we examine the role of situation-specific motivational profiles in the effectiveness of video modeling examples for learning problem-solving and self-assessment accuracy in the domain of biology. A sample of 342 secondary school students participated in our study. Latent profile...
Source: springer.com
Using GPT-2 to generate Tweets
Last summer I blogged about using a Deep Neural Network to generate tweets but only used 3200 of my tweets. Since then I've used Twitter's archive mechanism to retrieve ALL my tweets (just over 30,000) to train a network. Not any old network - the GPT-2 model from OpenAI. This 'finetuning' of an existing...
Google must face $5B lawsuit over tracking private internet use, judge rules
Judge finds tech giant didn't notify users their data could still be collected in incognito mode.
Source: cnet.com
Validation of Claims-Based Algorithms to Identify Patients with Psoriasis - PubMed Pharmacoepidemiology and drug safety.
Claims-based algorithms based on a combination of PsO diagnosis codes and dispensing for PsO-specific treatments had a moderate-to-high PPV. These algorithms can serve as a useful tool to identify patients with PsO in future real-world data pharmacoepidemiologic studies. This article is protected by...
Source: nih.gov
Volvo Cars to go fully electric by 2030
"The Swedish firm is to phase out all models with internal combustion engines over the next few years."
Source: bbc.com
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