Thinking Allowed

medical / technology / education / art / flub

Drug therapy for delirium in terminally ill adults. Cochrane review.

Drug therapy for delirium in terminally ill adults.

"terminally ill adults includes anyone with an advanced progressive illness such as advanced cancer, advanced dementia or organ failure, as well as those receiving hospice and end-of-life care ... "

"We found low-quality evidence that, compared to placebo, drug therapy (specifically haloperidol and risperidone) may slightly worsen delirium symptoms in terminally ill people with delirium of mild to moderate severity. We found low- to moderate-quality evidence that these drugs may slightly increase adverse side effects. Given the small numbers of studies and participants on which current evidence is based, further research is essential."

Source: www.cochrane.org

delirium terminally ill advanced therapy adults drug slightly