Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16%...
Source: nature.com
Overturning 'conventional wisdom' with 'natural experiments'
Via Reuters ... "Economists David Card, Joshua Angrist and Guido Imbens won the 2021 Nobel economics prize on Monday for pioneering "natural experiments" to show real-world economic impacts in areas from minimum wage increases in the U.S. fast-food sector to migration from Castro-era Cuba." "One experiment...
Source: reuters.com
Using Markov chain model to evaluate medical students’ trajectory on progress tests and predict USMLE step 1 scores---a
Background Medical students must meet curricular expectations and pass national licensing examinations to become physicians. However, no previous studies explicitly modeled stages of medical students acquiring basic science knowledge. In this study, we employed an innovative statistical model to characterize...
Source: biomedcentral.com
Can ultrasound novices develop image acquisition skills after reviewing online ultrasound modules? Elaine Situ-LaCasse.
Background Point-of-care ultrasound is becoming a ubiquitous diagnostic tool, and there has been increasing interest to teach novice practitioners. One of the challenges is the scarcity of qualified instructors, and with COVID-19, another challenge is the difficulty with social distancing between learners...
Source: biomedcentral.com
Covid bereavement group founder is 'inspirational young man'
Covid bereavement group founder is 'inspirational young man': The support group now has about 700 members around the UK and beyond. "On the evening of his father's funeral Liam Meyer launched a group to help other families whose lives had been ravaged by Covid-19. His father, David, died with Covid-19...
Source: bbc.com
11 TOPS photonic convolutional accelerator for optical neural networks: Convolutional neural networks, inspired by biological
11 TOPS photonic convolutional accelerator for optical neural networks: Convolutional neural networks, inspired by biological visual cortex systems, are a powerful category of artificial neural networks that can extract the hierarchical features of raw data to provide greatly reduced parametric complexity...
Source: nature.com
Preparing Future Psychiatrists in the Era of Apps and Chatbots
Therapy and E-therapy—Preparing Future Psychiatrists in the Era of Apps and Chatbots David Gratzer. David Goldbloom. Academic Psychiatry.
Source: springer.com
Milasen - a drug developed for a single patient.
Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease | NEJM: Summary Genome sequencing is often pivotal in the diagnosis of rare diseases, but many of these conditions lack specific treatments. We describe how molecular diagnosis of a rare, fatal neurodegenerative condition led to the...
Source: nejm.org
Climate change 'greatest threat', UN told: Naturalist Sir David Attenborough says climate change is humanity's greatest
Climate change 'greatest threat', UN told: Naturalist Sir David Attenborough says climate change is humanity's greatest threat in thousands of years.
Source: bbc.com
Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement: This 2018 Recommendation
Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement: This 2018 Recommendation Statement from the US Preventive Services Task Force recommends screening for osteoporosis with bone measurement testing to prevent osteoporotic fractures in women 65...
Source: jamanetwork.com
Management Reasoning: Beyond the Diagnosis: This Viewpoint discusses management reasoning, ways in which it differs from
Management Reasoning: Beyond the Diagnosis: This Viewpoint discusses management reasoning, ways in which it differs from diagnostic reasoning, and areas that require further research. David A. Cook. Jonathan Sherbino. Steven J. Durning. JAMA.
Source: jamanetwork.com
The Greatest Failure in What used to be Called Medicine | Dr. David Healy
The Greatest Failure in What used to be Called Medicine | Dr. David Healy
Source: davidhealy.org
Computer model for the cardiovascular system: development of an e-learning tool for teaching of medical students: This study
Computer model for the cardiovascular system: development of an e-learning tool for teaching of medical students: This study combined themes in cardiovascular modelling, clinical cardiology and e-learning to create an on-line environment that would assist undergraduate medical students in understanding...
Source: biomedcentral.com
Insulin Pumps Tied to Fewer Type 1 Diabetes Complications in Young Patients: By Amy Orciari Herman Edited by David G.
Insulin Pumps Tied to Fewer Type 1 Diabetes Complications in Young Patients: By Amy Orciari Herman
Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM
Young patients with type 1 diabetes may experience fewer disease complications with insulin pump therapy than with multiple...
Source: jwatch.org
Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case–control study: In a matched
Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case–control study: In a matched case-control-study among patients in Ontario, Canada treated with opioid painkillers, Tara Gomes and colleagues investigate whether co-prescription of gabapentin is associated with...
Source: plos.org
Adult learning theories: Implications for learning and teaching in medical education: AMEE Guide No. 83: There are many
Adult learning theories: Implications for learning and teaching in medical education: AMEE Guide No. 83: There are many theories that explain how adults learn and each has its own merits. This Guide explains and explores the more commonly used ones and how they can be used to enhance student and faculty...
Source: tandfonline.com
Collaborative Care Linked to Better Outcomes in Substance Use Disorders: By Kelly Young Edited by David G. Fairchild,
Collaborative Care Linked to Better Outcomes in Substance Use Disorders: By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD
Patients with alcohol or opioid use disorder treated with a collaborative care model in primary care are twice as likely to receive evidence-based...
Source: jwatch.org
Low‐cost agricultural waste accelerates tropical forest regeneration: Lower‐cost tropical forest restoration methods,
Low‐cost agricultural waste accelerates tropical forest regeneration: Lower‐cost tropical forest restoration methods, particularly those framed as win–win business‐protected area partnerships, could dramatically increase the scale of tropical forest restoration activities,... Treuer, Timothy...
Source: wiley.com
Continuous Glucose Monitoring May Improve Glucose Control in Type 2 Diabetes Requiring Insulin: By Kelly Young Edited
Continuous Glucose Monitoring May Improve Glucose Control in Type 2 Diabetes Requiring Insulin: By Kelly Young
Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD
Among patients with type 2 diabetes, continuous glucose monitoring is associated with better glucose control, according...
Source: jwatch.org
WHO: 12 Bacteria Families Urgently Require New Antibiotics: By Kelly Young Edited by David G. Fairchild, MD, MPH The
WHO: 12 Bacteria Families Urgently Require New Antibiotics: By Kelly Young
Edited by David G. Fairchild, MD, MPH
The World Health Organization has listed 12 families of bacteria that "pose the greatest threat to human health" because of resistance to … NEJM Journal Watch.
Source: jwatch.org
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